Correction to Optimized Fragmentation Regime for Diazirine Photo-Cross-Linked Peptides

I our paper entitled “Optimized Fragmentation Regime for Diazirine Photo-Cross-Linked Peptides”, there are two separate textual errors, one in Figure 6B (and repeated in the TOC graphic) and one in the Data Analysis section. Results: Decision tree representation (Figure 6B and TOC graphic) In Figure 6B and again in the TOC graphic, a visual decision tree was created from the m/z binning in Figure 4D (compare also Supporting Information Figure S2). Unfortunately, an algorithmic error introduced an offset of 200 m/z in the representation of the decision tree. The decision tree is corrected here (Figure 6B). Data Analysis The used modification masses were partly not correctly stated. Instead, the following modification masses are the correct ones: “SDA” cross-link, 82.0418 Da (C5H6O); “SDA-loop”, 82.0418 Da (C5H6O); “SDA-hydro”, 100.0524 Da (C5H8O2). The reaction scheme in Figure S9 shows the derivation of these masses. During our database search, however, we used the correct masses for the cross-linker reaction between two peptides (“SDA”, 82.0418 Da) as well as for the “SDA-loop” (82.0418 Da). The “SDA-hyd” modification mass was not used in the database search.